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Longxin Pharmaceutical

Scaling and insufficient temperature control precision in the circulating water system during carboxylation and acid precipitation processes.

Longxin Pharma Reactor Site

Issue

Situation before processing

Scaling in the reactor jacket during carboxylation and acid precipitation of pharmaceutical intermediates reduces temperature control precision and compromises batch stability.

Instructions

Installation Location & Plan

Install equipment on the process circulating water main header to cover reactor jackets and coolers.

Acceptance and Operational Performance

Restored temperature control accuracy, improved batch stability, and reduced cleaning frequency.

Note: Project outcomes depend on water quality, operating conditions, and management practices. This case study illustrates the approach for similar systems only and does not constitute a guarantee of results for specific projects.

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